Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays, Proposed Guideline, ILA29AE

Published by	Publication Date	Number of Pages
CLSI	01/01/2008	64

Category: CLSI

Description

CLSI I/LA29-A – Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays, Proposed Guideline, ILA29AE

The current and emerging technologies for detecting and characterizing human leukocyte antigen (HLA) alloantibodies providepowerful tools for predicting the risk of immunological response to a transplant. Clinical and Laboratory Standards Institutedocument I/LA29-A–Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays; Approved Guidelinedescribes criteria for optimizing methods that utilize flow cytometry and other conventional and multiplex platforms. Theintended audience includes solid organ and stem cell transplant laboratories, manufacturers of systems for histocompatibilitytesting, and organizations that manage organ sharing.